While the benefits of berberine are compelling, it’s not without side effects. Common issues include digestive discomfort, such as diarrhea, constipation, or stomach cramps, especially at higher doses. Berberine may also interact with medications, including metformin, statins, or blood thinners, potentially amplifying their effects. For example, combining berberine with diabetes drugs could lead to low blood sugar.
Pregnant or breastfeeding women should avoid berberine due to limited safety data. Always consult a healthcare provider before starting berberine, especially if you’re on medications or have underlying conditions.
How to Use Berberine Safely
To maximize the benefits of berberine, take it as directed, typically 500 mg two to three times daily with meals to reduce digestive side effects. Start with a lower dose to assess tolerance. Choose high-quality supplements from reputable brands to ensure purity. Pair berberine with a balanced diet and lifestyle for optimal results.